Perspectives on Anti-Inflammatory Drugs Inflammation is a very complicated process of interrelated events and cas- cades that does not allow for an easily defined, focused attack for drug discovery. It is evident from years of research and development that certain classes of compounds (e.g., NSAIDs, steroids, and so on) have had a meas- ure of success in alleviating pain and even dampening cellularlhormonal mechanisms involved in the process. Clear, mechanism-related therapies (e.g., for arthritis) and targeted drugs (e.g., for transplantation) have not been available in the past and, in reality,.
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Vincent J. Merluzzi, Julian Adams The Search for Anti-Inflammatory Drugs: Case Histories from Concept to Clinic free
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